Oct142022

Antibody Persistence and Booster Response in Adolescents and Young Adults 4 and 7.5 Years After Immunization with 4CMenB Vaccine

Recent Publications

Data on duration of protection against invasive meningococcal disease post-vaccination with the recombinant, 4-component, meningococcal serogroup B vaccine (4CMenB) are limited. We evaluated bactericidal activity persistence in adolescents/young adults up to 7.5 years post-primary vaccination with 4CMenB, and response to a booster dose compared with vaccine-naïve controls.  This open-label, multicentre study enrolled 15-24 year-old-previously vaccinated…

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Oct142022

Locally Delivered Flurbiprofen 8.75 mg for Treatment and Prevention of Sore Throat: A Narrative Review of Clinical Studies

Recent Publications

Antibiotics are inappropriately prescribed to many people with sore throat. As most cases of sore throat are viral and/or self-limiting, guidelines recommend symptomatic management as first-line treatment. This paper reviews the available clinical evidence for the efficacy and safety of low dose (8.75 mg) flurbiprofen, locally delivered to the throat for the symptomatic management of…

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Oct142022

A New Fully Liquid Presentation of MenACWY-CRM Conjugate Vaccine: Results from a Multicentre, Randomised, Controlled, Observer-Blind Study

Recent Publications

The currently licensed quadrivalent MenACWY-CRM conjugate vaccine presentation consists of two vials (lyophilised MenA and liquid MenCWY) to be reconstituted before injection. A new fully liquid formulation in a single vial has been developed to further improve the vaccine presentation. Since the MenA structure is subject to hydrolytic degradation, this study was conducted to compare…

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Oct142022

Clinical Characteristics of People with Heart Failure in Australian General Practice: Results from a Retrospective Cohort Study

Recent Publications

This study analysed anonymised patient data extracted from the clinical software of 43 participating GP clinics for the 5-year period from 1 July 2013 to 30 June 2018. Patients were stratified into ‘definite’ and ‘probable’ HF based on a hierarchy of selection criteria and analysed for their clinical characteristics. Symptoms and signs of HF and…

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