Atrial Fibrillation (AF) and Atrial Flutter (AFL) are common heart rhythm disorders that can increase the risk of various health complications. An estimated 2.2% of the general practice patient population in Australia in 2019 were diagnosed with AF. Potential health risks associated with AF include: Stroke: In atrial fibrillation, the irregular heartbeats can cause blood…
This paper presents the result from a randomised, double-blind study in adults with sore throat due to upper respiratory tract infection who took flurbiprofen (n = 249) or placebo spray (n = 256). Pain relief was assessed using the Sore Throat Relief Rating Scale. In this study, flurbiprofen spray provided significantly greater relief versus placebo…
Data on duration of protection against invasive meningococcal disease post-vaccination with the recombinant, 4-component, meningococcal serogroup B vaccine (4CMenB) are limited. We evaluated bactericidal activity persistence in adolescents/young adults up to 7.5 years post-primary vaccination with 4CMenB, and response to a booster dose compared with vaccine-naïve controls. This open-label, multicentre study enrolled 15-24 year-old-previously vaccinated…
The currently licensed quadrivalent MenACWY-CRM conjugate vaccine presentation consists of two vials (lyophilised MenA and liquid MenCWY) to be reconstituted before injection. A new fully liquid formulation in a single vial has been developed to further improve the vaccine presentation. Since the MenA structure is subject to hydrolytic degradation, this study was conducted to compare…
